FAQs
Frequently Asked Questions—
Aesthetics
*These statements have not been evaluated by the FDA. Innate Healthcare Institute is a private clinic and any treatments utilizing any form of regenerative medicine is considered experimental.
What is PRP microneedling with UC-MSC derived exosomes?
Microneedling is a cosmetic treatment that involves using a device with tiny needles to puncture the skin and create micro-injuries. This triggers the skin’s natural healing process, leading to the production of collagen and elastin, which can improve the appearance of fine lines, wrinkles, scars, and stretch marks.
Platelet-rich plasma (PRP) is a concentration of platelets in a small amount of plasma, which is obtained by drawing a sample of a person’s own blood, processing it to concentrate the platelets, and then re-injecting it into the same person. PRP contains growth factors that promote healing and tissue regeneration.
UC-MSC derived exosomes are tiny vesicles that are produced and secreted by umbilical cord mesenchymal stem cells (UC-MSCs). They contain a variety of bioactive molecules, such as RNA, proteins, and lipids, that can regulate cellular processes, such as proliferation, differentiation, and migration, and can help to improve the appearance of skin.
In PRP microneedling with UC-MSC derived exosomes, the PRP is combined with exosomes derived from UC-MSCs, and the mixture is then applied to the skin before microneedling. The microneedling process creates channels for the PRP mixture to penetrate deeper into the skin, where it can promote healing and rejuvenation. The UC-MSC derived exosomes are believed to enhance the effects of the PRP by providing additional bioactive molecules to the skin.
It’s important to note that this treatment is considered cosmetic and has not been thoroughly studied or approved by regulatory bodies, such as the FDA. As with any cosmetic procedure, it is important to consult with a qualified healthcare provider and discuss the potential risks and benefits before undergoing treatment.
How do Umbilical cord mesenchymal stem cells, and their exosomes, help with aging skin?
UC-MSCs are a type of stem cell that can differentiate into various cell types, such as osteocytes, chondrocytes, and adipocytes. They also secrete a variety of bioactive molecules, such as growth factors, cytokines, and exosomes, which can help to regulate cellular processes and promote tissue repair and regeneration.
Exosomes are small vesicles that are produced and secreted by UC-MSCs and other cells. They contain a variety of bioactive molecules, such as RNA, proteins, and lipids, which can regulate cellular processes, such as proliferation, differentiation, and migration. Exosomes derived from UC-MSCs have been shown to contain growth factors, such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), that can promote tissue repair and regeneration, and to have anti-inflammatory and antioxidant effects.
In the context of aging skin, UC-MSCs and their exosomes are thought to help improve the appearance of aging skin by promoting the production of collagen and elastin, which are the proteins responsible for skin elasticity, and by regulating cellular processes that contribute to skin aging, such as oxidative stress and inflammation. By promoting tissue repair and regeneration, UC-MSCs and their exosomes may help to improve the appearance of fine lines, wrinkles, and other signs of aging.
It’s important to note that the use of UC-MSCs and their exosomes in cosmetic procedures, including for aging skin, is still in the early stages of research and has not been thoroughly studied or approved by regulatory bodies, such as the FDA. As with any cosmetic procedure, it is important to consult with a qualified healthcare provider and discuss the potential risks and benefits before undergoing treatment.
What is an aesthetic chemical peel?
A chemical peel is a cosmetic treatment that uses a solution to remove the top layers of skin, resulting in the improvement of the skin’s appearance. Chemical peels are commonly used to treat various skin conditions, including acne, acne scarring, hyperpigmentation, fine lines and wrinkles, sun damage, and rough or uneven skin texture.
There are several types of chemical peels, including:
- AHA (alpha-hydroxy acid) peels: These peels use mild acids, such as glycolic acid, to gently exfoliate the skin and improve its texture and tone.
- BHA (beta-hydroxy acid) peels: These peels use salicylic acid to penetrate deep into the pores and remove impurities, making them a good option for those with oily or acne-prone skin.
- TCA (trichloroacetic acid) peels: These peels use a stronger acid to penetrate deeper into the skin, making them effective for treating more severe skin conditions, such as deep wrinkles, sun damage, and acne scarring.
- Phenol peels: These are the strongest type of chemical peel and are used to treat severe sun damage, deep wrinkles, and other severe skin conditions.
During a chemical peel, the solution is applied to the skin and left on for a specified amount of time, depending on the type of peel and the desired results. The solution then causes the top layers of skin to peel off, revealing smoother, more even-toned, and more youthful-looking skin.
It’s important to note that chemical peels can cause side effects, including redness, itching, burning, and peeling of the skin. It’s also important to choose a qualified and experienced aesthetician or dermatologist to perform the treatment to minimize the risk of complications. Before undergoing a chemical peel, it’s important to discuss the potential risks and benefits with a healthcare provider and ensure that the treatment is appropriate for your individual needs and skin type.
How can UC-MSC exosomes improve skin firming, texture, tone?
What growth factors do UC-MSC exosomes have to regenerate skin?
UC-MSC exosomes are known to contain a variety of growth factors and signaling molecules that can help to regenerate skin. Some of the growth factors found in UC-MSC exosomes include:
- Platelet-Derived Growth Factor (PDGF) – promotes cell proliferation and wound healing.
- Vascular Endothelial Growth Factor (VEGF) – stimulates angiogenesis and blood vessel formation.
- Transforming Growth Factor-β (TGF-β) – involved in the regulation of cell growth and differentiation, as well as the healing of wounds.
- Fibroblast Growth Factor (FGF) – plays a role in the regulation of cell proliferation, migration, and differentiation.
- Insulin-Like Growth Factor (IGF) – involved in the regulation of cell growth, differentiation, and metabolism.
These growth factors are believed to promote the growth and proliferation of new skin cells, as well as stimulate the formation of new blood vessels, which can help to improve skin health and appearance. However, it’s important to note that the exact effects of these growth factors on the skin are still being studied and more research is needed to fully understand their mechanisms of action.
How do stem cells and exosomes rejuvenate hair growth?
Stem cells have the ability to differentiate into various cell types, including hair follicle cells, and to secrete bioactive molecules that regulate cellular processes, such as cell proliferation, differentiation, and migration. By promoting the growth of new hair follicles and the maintenance of existing hair follicles, stem cells may help to rejuvenate hair growth.
Exosomes are small vesicles that are produced and secreted by stem cells and other cells. They contain a variety of bioactive molecules, such as RNA, proteins, and lipids, which can regulate cellular processes. Exosomes derived from stem cells have been shown to contain growth factors, such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), that can promote tissue repair and regeneration, and to have anti-inflammatory and antioxidant effects.
In the context of hair growth, exosomes may help to rejuvenate hair growth by regulating the processes involved in hair follicle development and maintenance, such as cell proliferation, differentiation, and migration. By promoting the growth of new hair follicles and the maintenance of existing hair follicles, exosomes may help to improve hair growth and density.
It’s important to note that the use of stem cells and exosomes for the rejuvenation of hair growth is still in the early stages of research and has not been thoroughly studied or approved by regulatory bodies, such as the FDA. As with any cosmetic procedure, it is important to consult with a qualified healthcare provider and discuss the potential risks and benefits before undergoing treatment.
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